bone morphogenetic protein 7
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone, kidney and brown adipose tissue development. Additionally, this protein induces ectopic bone formation and may promote fracture healing in human patients. [provided by RefSeq, Jul 2016].
Ask anything about BMP7 — pathways, variants, literature, experimental design. Free for researchers, 30,000 AI tokens daily.
Ask AI about BMP7 →Data source: NCBI Gene · alsesAI Gene Library