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BNIP3 gene

BCL2 interacting protein 3

Key facts

Official symbol
BNIP3
Full name
BNIP3
Chromosome
10
Map location
10q26.3
Organism
Homo sapiens
NCBI Gene ID
664
Also known as
HABON, NIP3

Function summary

This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014].

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Data source: NCBI Gene · alsesAI Gene Library