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CHUK gene

component of inhibitor of nuclear factor kappa B kinase complex

Key facts

Official symbol
CHUK
Full name
CHUK
Chromosome
10
Map location
10q24.31
Organism
Homo sapiens
NCBI Gene ID
1147
Also known as
BPS2, IKBKA, IKK-1, IKK-alpha, IKK1, IKKA

Function summary

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor. [provided by RefSeq, Jul 2008].

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Data source: NCBI Gene · alsesAI Gene Library