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CXCL10 gene

C-X-C motif chemokine ligand 10

Key facts

Official symbol
CXCL10
Full name
CXCL10
Chromosome
4
Map location
4q21.1
Organism
Homo sapiens
NCBI Gene ID
3627
Also known as
C7, IFI10, INP10, IP-10, SCYB10, crg-2

Function summary

This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020].

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Data source: NCBI Gene · alsesAI Gene Library