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CYLD gene

CYLD lysine 63 deubiquitinase

Key facts

Official symbol
CYLD
Full name
CYLD
Chromosome
16
Map location
16q12.1
Organism
Homo sapiens
NCBI Gene ID
1540
Also known as
BRSS, CDMT, CYLD1, CYLDI, EAC, FTDALS8

Function summary

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

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Data source: NCBI Gene · alsesAI Gene Library