epithelial cell adhesion molecule
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008].
Ask anything about EPCAM — pathways, variants, literature, experimental design. Free for researchers, 30,000 AI tokens daily.
Ask AI about EPCAM →Data source: NCBI Gene · alsesAI Gene Library