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FASN gene

fatty acid synthase

Key facts

Official symbol
FASN
Full name
FASN
Chromosome
17
Map location
17q25.3
Organism
Homo sapiens
NCBI Gene ID
2194
Also known as
FAS, OA-519, SDR27X1

Function summary

The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008].

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Data source: NCBI Gene · alsesAI Gene Library