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FCGR2B gene

Fc gamma receptor IIb

Key facts

Official symbol
FCGR2B
Full name
FCGR2B
Chromosome
1
Map location
1q23.3
Organism
Homo sapiens
NCBI Gene ID
2213
Also known as
CD32, CD32B, FCG2, FCGR2, IGFR2

Function summary

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

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Data source: NCBI Gene · alsesAI Gene Library