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GCKR gene

glucokinase regulator

Key facts

Official symbol
GCKR
Full name
GCKR
Chromosome
2
Map location
2p23.3
Organism
Homo sapiens
NCBI Gene ID
2646
Also known as
FGQTL5, GKRP

Function summary

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008].

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Data source: NCBI Gene · alsesAI Gene Library