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HTRA1 gene

HtrA serine peptidase 1

Key facts

Official symbol
HTRA1
Full name
HTRA1
Chromosome
10
Map location
10q26.13
Organism
Homo sapiens
NCBI Gene ID
5654
Also known as
ARMD7, CADASIL2, CARASIL, CARASIL2, HtrA, L56

Function summary

This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008].

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Data source: NCBI Gene · alsesAI Gene Library