inhibitor of nuclear factor kappa B kinase subunit epsilon
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009].
Ask anything about IKBKE — pathways, variants, literature, experimental design. Free for researchers, 30,000 AI tokens daily.
Ask AI about IKBKE →Data source: NCBI Gene · alsesAI Gene Library