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IL2RG gene

interleukin 2 receptor subunit gamma

Key facts

Official symbol
IL2RG
Full name
IL2RG
Chromosome
X
Map location
Xq13.1
Organism
Homo sapiens
NCBI Gene ID
3561
Also known as
CD132, CIDX, IL-2RG, IMD4, P64, SCIDX

Function summary

The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010].

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Data source: NCBI Gene · alsesAI Gene Library