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JCHAIN gene

joining chain of multimeric IgA and IgM

Key facts

Official symbol
JCHAIN
Full name
JCHAIN
Chromosome
4
Map location
4q13.3
Organism
Homo sapiens
NCBI Gene ID
3512
Also known as
IGCJ, IGJ, JCH

Function summary

Enables IgA binding activity and protein homodimerization activity. Contributes to several functions, including immunoglobulin receptor binding activity; peptidoglycan binding activity; and phosphatidylcholine binding activity. Involved in several processes, including defense response to other organism; glomerular filtration; and positive regulation of respiratory burst. Located in extracellular space. Part of monomeric IgA immunoglobulin complex; pentameric IgM immunoglobulin complex; and secretory dimeric IgA immunoglobulin complex. [provided by Alliance of Genome Resources, Apr 2022]

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Data source: NCBI Gene · alsesAI Gene Library