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KCNH2 gene

potassium voltage-gated channel subfamily H member 2

Key facts

Official symbol
KCNH2
Full name
KCNH2
Chromosome
7
Map location
7q36.1
Organism
Homo sapiens
NCBI Gene ID
3757
Also known as
ERG-1, ERG1, H-ERG, HERG, HERG1, Kv11.1

Function summary

This gene encodes a component of a voltage-activated potassium channel found in cardiac muscle, nerve cells, and microglia. Four copies of this protein interact with one copy of the KCNE2 protein to form a functional potassium channel. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, May 2022].

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Data source: NCBI Gene · alsesAI Gene Library