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KLF11 gene

KLF transcription factor 11

Key facts

Official symbol
KLF11
Full name
KLF11
Chromosome
2
Map location
2p25.1
Organism
Homo sapiens
NCBI Gene ID
8462
Also known as
FKLF, FKLF1, MODY7, TIEG2, Tieg3

Function summary

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].

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Data source: NCBI Gene · alsesAI Gene Library