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MCL1 gene

MCL1 apoptosis regulator, BCL2 family member

Key facts

Official symbol
MCL1
Full name
MCL1
Chromosome
1
Map location
1q21.2
Organism
Homo sapiens
NCBI Gene ID
4170
Also known as
BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1

Function summary

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010].

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Data source: NCBI Gene · alsesAI Gene Library