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PFKL gene

phosphofructokinase, liver type

Key facts

Official symbol
PFKL
Full name
PFKL
Chromosome
21
Map location
21q22.3
Organism
Homo sapiens
NCBI Gene ID
5211
Also known as
ATP-PFK, PFK-B, PFK-L

Function summary

This gene encodes the liver (L) subunit of an enzyme that catalyzes the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate, which is a key step in glucose metabolism (glycolysis). This enzyme is a tetramer that may be composed of different subunits encoded by distinct genes in different tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].

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Data source: NCBI Gene · alsesAI Gene Library