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SAMHD1 gene

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

Key facts

Official symbol
SAMHD1
Full name
SAMHD1
Chromosome
20
Map location
20q11.23
Organism
Homo sapiens
NCBI Gene ID
25939
Also known as
CHBL2, DCIP, HDDC1, MOP-5, SBBI88, hSAMHD1

Function summary

This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010].

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Data source: NCBI Gene · alsesAI Gene Library