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SNAI2 gene

snail family transcriptional repressor 2

Key facts

Official symbol
SNAI2
Full name
SNAI2
Chromosome
8
Map location
8q11.21
Organism
Homo sapiens
NCBI Gene ID
6591
Also known as
SLUG, SLUGH, SLUGH1, SNAIL2, WS2D

Function summary

This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008].

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Data source: NCBI Gene · alsesAI Gene Library