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SPRED1 gene

sprouty related EVH1 domain containing 1

Key facts

Official symbol
SPRED1
Full name
SPRED1
Chromosome
15
Map location
15q14
Organism
Homo sapiens
NCBI Gene ID
161742
Also known as
LGSS, NFLS, PPP1R147, hSpred1, spred-1

Function summary

The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008].

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Data source: NCBI Gene · alsesAI Gene Library