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TCF7L2 gene

transcription factor 7 like 2

Key facts

Official symbol
TCF7L2
Full name
TCF7L2
Chromosome
10
Map location
10q25.2-q25.3
Organism
Homo sapiens
NCBI Gene ID
6934
Also known as
TCF-4, TCF4

Function summary

This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010].

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Data source: NCBI Gene · alsesAI Gene Library