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TPH2 gene

tryptophan hydroxylase 2

Key facts

Official symbol
TPH2
Full name
TPH2
Chromosome
12
Map location
12q21.1
Organism
Homo sapiens
NCBI Gene ID
121278
Also known as
ADHD7, NTPH

Function summary

This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016].

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Data source: NCBI Gene · alsesAI Gene Library