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UGT2B7 gene

UDP glucuronosyltransferase family 2 member B7

Key facts

Official symbol
UGT2B7
Full name
UGT2B7
Chromosome
4
Map location
4q13.2
Organism
Homo sapiens
NCBI Gene ID
7364
Also known as
UDPGT 2B7, UDPGT 2B9, UDPGT2B7, UDPGTH2, UDPGTh-2, UGT2B9

Function summary

The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017].

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Data source: NCBI Gene · alsesAI Gene Library