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ULK1 gene

unc-51 like autophagy activating kinase 1

Key facts

Official symbol
ULK1
Full name
ULK1
Chromosome
12
Map location
12q24.33
Organism
Homo sapiens
NCBI Gene ID
8408
Also known as
ATG1, ATG1A, UNC51, Unc51.1, hATG1

Function summary

Enables identical protein binding activity; protein serine/threonine kinase activity; and small GTPase binding activity. Involved in several processes, including autophagosome assembly; positive regulation by symbiont of host autophagy; and protein phosphorylation. Located in autophagosome; cytosol; and phagophore assembly site membrane. Is extrinsic component of autophagosome membrane; extrinsic component of omegasome membrane; and extrinsic component of phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. [provided by Alliance of Genome Resources, Apr 2022]

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Data source: NCBI Gene · alsesAI Gene Library