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WIF1 gene

Wnt inhibitory factor 1

Key facts

Official symbol
WIF1
Full name
WIF1
Chromosome
12
Map location
12q14.3
Organism
Homo sapiens
NCBI Gene ID
11197
Also known as
WIF-1

Function summary

The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010].

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Data source: NCBI Gene · alsesAI Gene Library