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CD40LG gene

CD40 ligand

Key facts

Official symbol
CD40LG
Full name
CD40LG
Chromosome
X
Map location
Xq26.3
Organism
Homo sapiens
NCBI Gene ID
959
Also known as
CD154, CD40L, HIGM1, IGM, IMD3, T-BAM

Function summary

The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008].

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Data source: NCBI Gene · alsesAI Gene Library