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SREBF2 gene

sterol regulatory element binding transcription factor 2

Key facts

Official symbol
SREBF2
Full name
SREBF2
Chromosome
22
Map location
22q13.2
Organism
Homo sapiens
NCBI Gene ID
6721
Also known as
SREBP-2, SREBP2, bHLHd2

Function summary

This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

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Data source: NCBI Gene · alsesAI Gene Library