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RSAD2 gene

radical S-adenosyl methionine domain containing 2

Key facts

Official symbol
RSAD2
Full name
RSAD2
Chromosome
2
Map location
2p25.2
Organism
Homo sapiens
NCBI Gene ID
91543
Also known as
SAND, cig33, cig5, vig1

Function summary

The protein encoded by this gene is an interferon-inducible antiviral protein that belongs to the S-adenosyl-L-methionine (SAM) superfamily of enzymes. The protein plays a role in cellular antiviral response and innate immune signaling. Antiviral effects result from inhibition of viral RNA replication, interference in the secretory pathway, binding to viral proteins and dysregulation of cellular lipid metabolism. The protein has been found to inhibit both DNA and RNA viruses, including influenza virus, human immunodeficiency virus (HIV-1) and Zika virus. [provided by RefSeq, Sep 2020].

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Data source: NCBI Gene · alsesAI Gene Library