WNK lysine deficient protein kinase 4
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.[provided by RefSeq, Sep 2009].
Ask anything about WNK4 — pathways, variants, literature, experimental design. Free for researchers, 30,000 AI tokens daily.
Ask AI about WNK4 →Data source: NCBI Gene · alsesAI Gene Library