MYCN proto-oncogene, bHLH transcription factor
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014].
Ask anything about MYCN — pathways, variants, literature, experimental design. Free for researchers, 20,000 AI tokens daily. /* batch156 */
Ask AI about MYCN →Data source: NCBI Gene · alsesAI Gene Library